These findings suggest that food insecurity is associated with differential gut microbial and metabolite composition for which the future implications are unknown. Metabolites related to energy transfer and gut–brain-axis communication (picolinic acid, phosphocreatine, 2-pyrrolidinone) were elevated in FI students ( q < 0.05). FI students experienced significantly greater microbial diversity with increased abundance of Enterobacteriaceae and Eisenbergiella, while FS students had greater abundance of Megasphaera and Holdemanella. Gut microbiome and metabolome were established using 16S rRNA amplicon sequencing, targeted liquid chromatography-tandem mass spectrometry, and gas chromatography-mass spectrometry. Fecal samples were collected up to 5 days post survey-completion. Students were dichotomized into food secure (FS) and food insecure (FI) groups using a validated, 2-question screener assessing food security status over the previous 30 days. In this study we compared the fecal microbiome and metabolome of racially and ethnically diverse first year college students ( n = 60) experiencing different levels of food access. However, these findings may not translate to food insecurity, where an individual experiences inconsistent access to healthy food options. Voluntary caloric restriction (e.g., eating disorders) often results in alterations in the gut microbiota composition and function.
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You can find the launch agents made by Keep Drive Spinning in the LaunchAgents folder of your user's Library folder. Launch agents are built-in OS X technology and persist across reboots, etc., so you can run this once to set-it-and-forget-it. This applet simply creates a launch agent that tells OS X to update a hidden file on the selected drive once every minute so that the drive stays awake. However, some external drives do not respect the System Preferences settings, so for them an alternative like this is needed. Normally this can be controlled using the Energy Saver preference pane in System Preferences, and that should be your first resort in dealing with the problem, rather than this or any other third party software. Keep Drive Spinning ensures that a connected drive never goes into low-power mode. 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